If I file a case against someone for spreading false information and damaging my reputation, can I get monetary compensation? And what about a separate case for the same issue? Which one would be more beneficial for me in the Indian legal system?

Yes, you can seek monetary compensation in India for defamation, which includes spreading false information that damages your reputation. Filing separate cases for the same issue is generally discouraged as it can be seen as forum shopping and may not be successful. It is advisable to consolidate all relevant claims within a single case for efficiency and stronger legal standing.